A New Role for Ran in Ensuring Precise Duplication of Chromosomal DNA
نویسنده
چکیده
To prevent re-replication of DNA, the licensing of replication origins is inhibited in S phase and G2. New work by Yamaguchi et al. (in this issue of Cell) shows that the small GTPase Ran can directly inhibit licensing inside nuclei once CDKs are active late in the cell cycle.
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ورودعنوان ژورنال:
- Cell
دوره 113 شماره
صفحات -
تاریخ انتشار 2003